660nm to 850nm Light – Deep Dive

This wavelength range includes:

  • 660nm (red light) – visible red

  • 810nm–850nm (near-infrared / NIR) – invisible but deeply penetrating

Both are non-ionizing, safe, and used in light therapy devices for brain health, performance, recovery, and even skin and mitochondrial function.

Mechanisms of Action

1. Mitochondrial Boosting (ATP Production)

  • These wavelengths stimulate cytochrome c oxidase (CCO) in the mitochondria.

  • CCO is part of the electron transport chain → this boosts ATP (cellular energy) production.

  • More ATP = better cellular repair, brain function, and resilience.

2. Increased Blood Flow

  • Light at these wavelengths triggers nitric oxide (NO) release.

  • This vasodilates blood vessels, improving oxygen and nutrient delivery to tissues (including the brain).

  • You get enhanced mental clarity, reduced fatigue, and better tissue healing.

3. Anti-inflammatory Effects

  • Red and NIR light reduce pro-inflammatory cytokines (IL-6, TNF-α).

  • Helps modulate immune response and calm systemic or neural inflammation—big for people with brain fog, depression, or chronic pain.

🧠 Brain-Specific Benefits (Especially 810–850nm)

🧬 1. Neuroprotection & Neurogenesis

  • 810nm–850nm penetrates the skull and brain tissue.

  • Promotes BDNF and NGF expression—hello, synergy with Lion’s Mane!

  • Encourages neurogenesis and helps protect against neurodegenerative processes (e.g., Alzheimer's, Parkinson’s).

Mood & Cognitive Enhancement

  • Increases serotonin and dopamine indirectly by reducing inflammation and increasing mitochondrial activity.

  • Users report better focus, mental energy, memory, and stress reduction.

Improved Sleep

  • Exposure to red light (especially 660nm) in the evening may help boost melatonin production naturally by reducing blue light exposure and supporting circadian rhythm.

Skin & Muscular Benefits (660nm-680nm)

  • Great for collagen production, wound healing, and reducing signs of aging.

  • Increases circulation in skin and superficial muscles.

  • Can help with muscle recovery, joint pain, and inflammation.

Wavelength Breakdown

Wave length Type Depth Best For 660nm Skin health, superficial tissues, inflammation 810nm NIR Deep Brain health, cognitive boost, neurogenesis 830-850nm NIR DeepJoint repair, muscle recovery, mitochondria

Note: 810nm is the sweet spot for transcranial photobiomodulation (brain-focused).

Tips & Usage

  • Daily or every other day use is common.

  • For brain: Place device at forehead/temples for ~10-20 mins.

  • For skin/muscle: Hold 6–12 inches from skin.

  • Don’t overdo it (there’s a biphasic dose response—too much can reduce benefits).

  • Pair with Lion’s Mane or other nootropics for a double neurotrophic whammy.

Photobiomodulation (PBM) for Dementia and Alzheimer's Disease

Mechanism of Action

  • Cellular Energy Production: PBM enhances mitochondrial activity, increasing ATP production. This supports cellular metabolism and promotes healing.

  • Reduced Inflammation: The treatment helps in modulating inflammatory responses, potentially reducing neuronal damage associated with Alzheimer’s.

  • Increased Neurotrophic Factors: It may stimulate the production of brain-derived neurotrophic factor (BDNF) and other neurotrophic factors that promote neuron survival and differentiation.

  • Enhanced Blood Flow: PBM can improve microcirculation, enhancing oxygen and nutrient supply to the brain, which is crucial for cognitive function.

Wavelengths and Effects

WavelengthEffects660 nm (Red Light)Penetrates tissue, useful for cell repair and anti-inflammatory effects. Supports cerebral circulation and can alleviate oxidative stress.850 nm (Near-Infrared)Penetrates deeper, promoting ATP production and neuroprotection. Enhances mitochondrial function, potentially slowing neurodegeneration.Far Infrared (FIR)Generally used to enhance overall circulation and promote relaxation. Less studied in specific dementia contexts but beneficial for overall well-being.

Benefits for Dementia and Alzheimer's

  • Cognitive Improvement: Preliminary studies show potential for improved cognitive functions, learning, and memory.

  • Neuroprotection: PBM may help protect neurons from further degeneration and toxicity often seen in Alzheimer's.

  • Potentially Slowing Disease Progression: Regular treatments could potentially slow the progression of cognitive decline.

Formation of New Neurons

  • Neurogenesis: Studies indicate that PBM can facilitate neurogenesis, particularly in the hippocampus, which is vital for learning and memory. The increase in BDNF levels associated with PBM is thought to underpin this process.

  • Mechanisms: PBM appears to upregulate pathways associated with neurotrophic factors, which promote the survival and growth of neurons. Enhanced mitochondrial function also supports cellular health, allowing for the potential regeneration of neuronal populations.